These three projects have been created by a collaboration between the Pande Group's Vincent Voelz and Lan Hua of the University of California, San Francisco. The units are distributed from the server 171.64.65.62.Project 6501 simulates Ubiquitin in an explicit solution. Ubiquitin is an important marker in the process of protein removal. A malfunction of this process is responsible for various diseases, including Parkinson's and Liddle's syndrome, and various cancers and viral infections. Project 6501 uses the Gromacs core and contains 25,933 atoms. Each unit is worth 123 points, with a preferred deadline of 23 days and final deadline of 34 days.
Ubiquitin structure diagram
Projects 6502 and 6503 simulate two areas (6502: domain A, residues 1-75; 6503: domain B, residues 77-143) of the PDB 2K5I protein which are involved in the transport of Iron (II). The protein was a target during the CASP8 challenge. Both projects use the Gromacs core. Project 6502 has 13,159 atoms, gives 59 points and has a preferred deadline of 11 days, with the final deadline 5 days later. Project 6503 has 17,092 atoms, and is worth 75 points. The preferred deadline is 14 days and the final deadline is 21 days.
These three projects will be unlikely to eliminate the current problems of WU shortages, but they help form part of the solution.
jmn
On: 04/20/10
