New A4 projects 7600, 7610 and 7611

By , the in Folding@Home Project - No comment
TJ Lane, a new grad student working with the Pande Group, has released three new projects using the A4 core: p7600, p7610 and p7611.

Project 7600 studies the folding of a knottin protein called EETI. This protein has been engineered so that it will bind to integrin proteins, which are found on the surface of cancerous cells. The EETI protein shows up on medical scans, so a cluster of EETI would indicate the presence of a tumor in the scan. The project aims to further understand how the protein works in order to aid development of similar proteins to target a variety of diseases.

The project has the following characteristics:
  • 12,377 atoms
  • 937 points
  • 13.92 day preferred deadline
  • 23.2 day final deadline
  • k factor of 0.75

The project is available to all uniprocessor and SMP clients on Windows and Linux. It is served from the server at 171.64.65.101.

Projects 7610 and 7611 study the FiP35 WW domain using very long trajectories from results from Shaw et al. (Science, 2010). These projects are intended to contrast the scientific methods used by Folding@home with more traditional methods, recently optimised by DE Shaw research.

The projects have the following characteristics:
  • 13,564 atoms
  • 788 points
  • 11.71 day preferred deadline
  • 19.52 day final deadline
  • k factor of 0.75

These projects are available to all uniprocessor and SMP clients on Windows and Linux, and are served from the server at 171.64.65.104.

Sources: p7600, p7610 and p7611